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). Aurora A plays a pivotal function in centrosome maturation and spindle formation in the course of mitosis. Therefore, inhibition of Aurora A activity with reduced concentrations of MLN8054 inhibits cells from progressing by mitosis Commonly and can result in aberrant mitotic spindle formation.Discovery of gramicidin A analogues with altered acti

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Th cells are affiliated with lipid synthesis and uptake and satisfy their metabolic requires through glycolysis, and Tregs are connected to FAO and OXPHOS. Lipids are strongly linked to tumor stemness, metastasis, and angiogenesis and therefore are important for the transformation of T-cell subpopulations. As a result, targeting lipid metabolism in

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